Directed evolution builds nanoparticles

Directed evolution is a powerful technique for engineering proteins. Scientists now show that it can also be used to engineer synthetic nanoparticles as optical biosensors, which are used widely in biology, drug development, and even medical diagnostics such as real-time monitoring of glucose. The 2018 Nobel Prize in Chemistry went to three scientists who developed … More Directed evolution builds nanoparticles

Incredibly’ diverse microbial community high in Yellowstone

More than 10 miles into the backcountry of Yellowstone National Park, on the edge of the caldera, lives a high-elevation community so diverse that scientists call it “incredible, unique and truly weird.” More than 10 miles into the backcountry of Yellowstone National Park, on the edge of the caldera, lives a high-elevation community so diverse … More Incredibly’ diverse microbial community high in Yellowstone

CRISPR reveals the secret life of antimicrobial peptides

Using CRISPR, scientists have carried out extensive work on a little-known yet effective weapon of the innate immune system, antimicrobial peptides. When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses. But our immune … More CRISPR reveals the secret life of antimicrobial peptides

Climate rewind: Scientists turn carbon dioxide back into coal

New technique can efficiently convert CO2 from gas into solid particles of carbon Scientists have harnessed liquid metals to turn carbon dioxide back into solid coal, in research that offers an alternative pathway for safely and permanently removing the greenhouse gas from our atmosphere. The new technique can convert CO2 back into carbon at room … More Climate rewind: Scientists turn carbon dioxide back into coal

Scientists direct bacteria with expanded genetic code to evolve extreme heat tolerance

Is nature’s 20 amino acid genetic code optimal-evolving proteins using an expanded genetic code? Synthetic bacteria with expanded genetic codes can evolve proteins in the laboratory with enhanced properties using mechanisms that might not be possible with nature’s 20 amino acid building blocks. Exposing bacteria with an artificially expanded genetic code to temperatures at which … More Scientists direct bacteria with expanded genetic code to evolve extreme heat tolerance

Correlated nucleons may solve 35-year-old mystery

A careful re-analysis of data taken as revealed a possible link between correlated protons and neutrons in the nucleus and a 35-year-old mystery. The data have led to the extraction of a universal function that describes the EMC Effect, the once-shocking discovery that quarks inside nuclei have lower average momenta than predicted, and supports an … More Correlated nucleons may solve 35-year-old mystery

How a certain bacterium communicates and makes us sick

Researchers have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design better ways to block and eventually control those toxins. Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative … More How a certain bacterium communicates and makes us sick

Manipulating gene expression in neurons with CRISPR

Neuron-optimized genome editing technology enables new ways to study genetic influences on brain health and disease Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. This technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that more closely resemble human conditions. … More Manipulating gene expression in neurons with CRISPR