Novel population-based approach to examine families where AF occurs with left atrial fibrosis

Atrial fibrillation (AF) is a condition that produces an irregular heartbeat that affects about two percent of the general population and six percent of people over 65 years of age. AF increases the risk of heart failure and stroke. While researchers have long believed genetics play a role in AF, decades of searching have revealed … More Novel population-based approach to examine families where AF occurs with left atrial fibrosis

Cilia and Flagella in Eukaryotes

Across all species, directed movement is essential for nutrient acquisition, energy harvesting, and the avoidance of danger or sources of stress. Organisms have evolved specific means of locomotion that are complementary to the environmental conditions that they live in. For example, air, land, and water have enabled the evolution of distinct locomotive methods: namely flying, … More Cilia and Flagella in Eukaryotes

New therapy targets gut bacteria to prevent and reverse food allergies

A new study identifies the species of bacteria in the human infant gut that protect against food allergies, finding changes associated with the development of food allergies and an altered immune response. Every three minutes, a food-related allergic reaction sends someone to the emergency room in the U.S. Currently, the only way to prevent a … More New therapy targets gut bacteria to prevent and reverse food allergies

Scientists delay aging using protein found in young mice

Scientists have shown that a protein which is abundant in the blood of young mice can delay the aging process and improve the activity levels of older mice. The study was carried out by researchers at the Washington University School of Medicine in St. Louis and the results were published in the journal Cell Metabolism … More Scientists delay aging using protein found in young mice

Study reveals genetic signature of failed immune response to cancer

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn’t act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, researchers from the University of Montreal Hospital Research Centre (CRCHUM) revealed the genetic signature of this failed immune response for the … More Study reveals genetic signature of failed immune response to cancer

RNR ‘switch’ offers hope in battling antibiotic resistant bacteria

New research offers a new pathway for targeting pathogens in the fight against antibiotic resistant bacteria. As antibiotic resistance rises, the search for new antibiotic strategies has become imperative. Researchers used the Cornell High Energy Synchotron Source (CHESS) to reveal an unexpected mechanism of activation and inactivation in the protein ribonucleotide reductase (RNR). The findings … More RNR ‘switch’ offers hope in battling antibiotic resistant bacteria

Virus genes help determine if pea aphids get their wings

Researchers shed light on the important role that microbial genes, like those from viruses, can play in insect and animal evolution. Many of an organism’s traits are influenced by cues from the organism’s environment. These features are known as phenotypically plastic traits and are important in allowing an organism to cope with unpredictable environments. But … More Virus genes help determine if pea aphids get their wings

Domino effect of species extinctions also damages biodiversity

The mutual dependencies of many plant species and their pollinators mean that the negative effects of climate change are exacerbated. The total number of species threatened with extinction is therefore considerably higher than predicted in previous models, researchers show. The mutual dependencies of many plant species and their pollinators mean that the negative effects of … More Domino effect of species extinctions also damages biodiversity

Viruses found to use intricate ‘treadmill’ to move cargo across bacterial cells

State-of-the-art technologies reveal bacterial cells organized like human cells, offering insights for new phage therapies on untreatable infections Using advanced technologies to explore the inner workings of bacteria, biologists have provided the first example of cargo within bacteriophage cells transiting along treadmill-like structures. The discovery demonstrates that bacteria have more in common with sophisticated human … More Viruses found to use intricate ‘treadmill’ to move cargo across bacterial cells

How multi-celled animals developed

New findings challenge the long-standing idea that multi-celled animals evolved from a single-celled ancestor resembling a modern sponge cell known as a choanocyte. Scientists at The University of Queensland have upended biologists’ century-old understanding of the evolutionary history of animals. Using new technology to investigate how multi-celled animals developed, their findings revealed a surprising truth. … More How multi-celled animals developed